Design and implementation of a head‐and‐neck phantom for system audit and verification of intensity‐modulated radiation therapy
نویسندگان
چکیده
The head and neck is a challenging anatomic site for intensity-modulated radiation therapy (IMRT), requiring thorough testing of planning and treatment delivery systems. Ideally, the phantoms used should be anatomically realistic, have radiologic properties identical to those of the tissues concerned, and allow for the use of a variety of devices to verify dose and dose distribution in any target or normaltissue structure. A phantom that approaches the foregoing characteristics has been designed and built; its specific purpose is verification for IMRT treatments in the head-andneck region. This semi-anatomic phantom, HANK, is constructed of Perspex (Imperial Chemical Industries, London, U.K.) and provides for the insertion of heterogeneities simulating air cavities in a range of fixed positions. Chamber inserts are manufactured to incorporate either a standard thimble ionization chamber (0.125 cm3: PTW, Freiburg, Germany) or a smaller PinPoint chamber (0.015 cm3: PTW), and measurements can be made with either chamber in a range of positions throughout the phantom. Coronal films can also be acquired within the phantom, and additional solid blocks of Perspex allow for transverse films to be acquired within the head region. Initial studies using simple conventional head-and-neck plans established the reproducibility of the phantom and the measurement devices to within the setup uncertainty of +/- 0.5 mm. Subsequent verification of 9 clinical head-and-neck IMRT plans demonstrated the efficacy of the phantom in making a range of patient-specific dose measurements in regions of dosimetric and clinical interest. Agreement between measured values and those predicted by the Pinnacle3 treatment planning system (Philips Medical Systems, Andover, MA) was found to be generally good, with a mean error on the calculated dose to each point of +0.2% (range: -4.3% to +2.2%; n = 9) for the primary planning target volume (PTV), -0.1% (range: -1.5% to +2.0%; n = 8) for the nodal PTV, and +0.0% (range: -1.8% to +4.3%, n = 9) for the spinal cord. The suitability of the phantom for measuring combined dose distributions using radiographic film was also evaluated. The phantom has proved to be a valuable tool in the development and implementation of clinical head-and-neck IMRT, allowing for accurate verification of absolute dose and dose distributions in regions of clinical and dosimetric interest.
منابع مشابه
Dosimetric verification of pre-treatment intensity modulated radiation therapy in the commissioning process
Background: Commissioning tests are recommended before implementing Intensity Modulated Radiation Therapy. This study evaluated five different plans of IMRT mocks for different modulation indices. Materials and Methods: IMRT tests were done in slab phantom for both 6MV and 15 MV photon energies using a 2D array ion chamber dosimeter. Results: The acceptance criteria were based on 3% /3mm. All t...
متن کاملComprehensive end-to-end test for intensity-modulated radiation therapy for nasopharyngeal carcinoma using an anthropomorphic phantom and EBT3 film
Background: In head and neck radiotherapy, immobilization devices can affect dose delivery. In this study, a comprehensive end-to-end test was developed to evaluate the accuracy of radiotherapy treatment. Materials and Methods: An Alderson Radiation Therapy (ART) anthropomorphic phantom with EBT3 film was used to mimic the actual patient treatment process. Ten patients treated for nasopharyngea...
متن کاملDesign and Implementation of Head and Neck Perspex Phantom for Intensity Modulated Radiation Therapy
The aims of this study are to design, construct and evaluate the applicability of a head and neck Perspex phantom for dosimetric verification of intensity modulated radiation therapy (IMRT). Thermoluminescent dosimeters (TLDs) was used in this study. Consistency of the fabricated phantom readings was checked by multiple IMRT irradiations. The inter-fraction standard deviation among all TLDs’ me...
متن کاملDose Distribution Analysis of Rapid Arc and Intensity Modulated Radiotherapy Plan in Head and Neck Cancer
Introduction: Globally, intensity-modulated radiation therapy (IMRT) is considered as highly precise and accurate method of radiotherapy planning. This technique amplifies spatial dose distribution conformity by modulating the intensity of radiation beams in each sub-volume. Additionally, it can reduces the dose to surrounding critical organs and deliver the planned dose to targets with the nom...
متن کاملUtilization of Electronic Portal Imaging Device (EPID) For Setup Verification and Determination of Setup Margin in Head and Neck Radiation Therapy
Introduction: Radiation therapy involves a multistep procedure; therefore, the error in patient set up is an inherent part of the treatment. Main purpose of this study was to determine the clinical target volume (CTV) to planning target volume (PTV) in head and neck cancer patients. Material and Methods: A total of 15 patients who had daily p...
متن کامل